INTRODUCTION:High
cholesterol is the best known of all
the many threats to a healthy heart.
When excess amounts of this waxy, fat-like
substance build up along the walls of
the arteries, you face a dramatically
higher risk of a complete blockage,
leading to a heart attack or stroke.
At normal levels, cholesterol is not
a bad thing. On the contrary, it's an
essential raw material used by the body
to build cell walls and produce hormones
such as estrogen and testosterone. The
body produces its own supply of cholesterol
in the liver, and it's found naturally
in all animal products (such as meats,
eggs, milk, and cheese). It poses a
problem only when the body is unable
to use or eliminate excessive supplies.
As one of a variety of fatty substances
in the body, cholesterol is classified
as a lipid. It is carried through the
bloodstream attached to proteins, forming
complexes called lipoproteins. There
are two major types of lipoproteins:
the low-density lipoproteins (LDL) commonly
known as "bad" cholesterol, and the
high-density lipoproteins (HDL) usually
dubbed "good" cholesterol. It's the
"bad" LDL cholesterol that tends to
form deposits on the artery walls. HDLs,
on the other hand, help to clear excess
cholesterol from the bloodstream. The
ideal situation to aim for, then, is
a low level of LDL cholesterol, a high
level of HDL cholesterol, and a moderate
total of both.
Cholesterol is measured in milligrams
per deciliter of blood. According to
the National Cholesterol Education Program,
a desirable target profile consists
of:
- A total blood cholesterol level
of less than 200
- An LDL level of:
- less than 100 if you have
heart disease
- less than 130 if you're at
risk of heart disease
- less than 160 if your risk
of heart disease is low
- An HDL level greater than 40
You are generally considered at risk
of heart disease if two or more of the
following factors apply to you:
- Cigarette smoking
- High blood pressure
- Low HDL cholesterol (below 40)
- A family history of early heart
disease (before 55 in a man, or
65 in a woman)
- Your own age (over 45 if you're
man, over 55 if you're a woman)
THE PRODUCT
:AV UNILIPID is a proprietary
formula that has been clinically proven
to be effective in incidence of Hypercholesterolemia.
COMPOSITION:
Each capsule of AV UNILIPID contains:
RESEARCH:
Clinical
Evaluation of The Hypolipidemic activity
of AV UNILIPID
Commiphora
mukul :
The gum of this herb has been studied
by over 100 clinical researchers,
all of whom have shown that the herb
has significant lipid lowering activity.
Based on ethnobotanical data and recent
scientific discoveries, we have included
this herb as part of the developmental
process. It was amongst 195 herbs
screened for activity.
Allium sativum:
Garlic as it is commonly called. Whilst
eating dietary garlic is recommended
it has several problems. The odor
is the major one as people’s skin
smell all day, but the other is the
stability of the herb. An enzyme contained
in the fresh bulbs break down the
activity ingredient to convert it.
By extracting and stabilizing these
active compound we have been able
to use this powerful herb in the formula.
Trigonella
foenum-graecum :
A common vegetable in India, the seeds
of this plant yield powerful bioactive
substances that help reduce cholesterol.
The herb also provides soluble dietary
fibers that help transport serum cholesterol
out of the system.
Piper Nigrum:
Used in all AV range of products,
this is a herb that enhances the Bioavailability
of other herbs. It makes the product
more effective.
DOSAGE:1
Capsule Thrice a day after meals.
CONTRAINDICATIONS:
None reported
PREGNANCY:
Safe during 1st & 2nd Trimester.
INDICATIONS:
- Hypercholesterolemia.
- Cardiovascular problems.
REFERENCES:
- Chemical Abstract, 72, 2454, 1970
: Thioglycosides are the biologically
active components of Garlic.
- Anti bacterial and anti fungal
Effects.
- Chem. Abstract 86, 16684 IP
1977 : Inhibits both growth,
congulass activity of S.Aureus.
Extract is much superior to
vol.oil obtained from Garlic.
- Indian Journal of Experimental
Biology 45(6), 1977, Pg.455
Extract quite effective in inhibitory
effect on many bacterial species.
- Biology Abstract 64, 37133,
1977 : Fungicidal & fungistatic
activity.
- Trease 11th ed. 1978 Pg.657.
- Biol.Abstact 49, 62157,1968 :
Anti coagulant action, this factor
in Garlic is non-volatile and has
hypoglycemic effect.
- American Journal of Clinical Nutrition,
28(7), 1975, Pg.684 Anti diabetic
activity : Garlic extracts found
hypoglycemic when given orally to
Allaxon diabetic rats.
- Indian Journal of Experimental
Biology 7, 1969, Pg.250 : Anti inflammatory
activity. Extract found effective
against carrageenin induced rat
hind paw & oedema in albino
rats.
- Biology Abstract 59, 16878, 1975
: Highly significant in increasing
gastric secretion.
- Hypotensive & hypocholesteralemic
activity.
- Indian Journal of Experimental
Biology 45(6), 1977, Pg.489
Oral administration of extract
for 2 months reduced lipid levels
in serum & liver.
- Biology Abstract 63, 84676,
1977 : Extract reduces arterial
blood pressure in rats, cats,
dogs & human beings.
- Chemical Abstract 66, 74825,
1967 : Supplementation in rabbits
fed with cholesterol, revealed
significant phospholipids and
thus reduction in athereosclerosis.
- International Cardio-Pulmonary
Symposium, Bombay, Indian Garlic
extract reduces serum cholestrol
level.
- Indian Drugs, August, 1978.
- 'Lehsun', Nai Dunia, Indore,
Dec.19, 1978.
- S.Bhusan et al, Journal of Physical
Pharmacology, 1979, Pg.211 Effect
of Garlic in normal blood cholesterol
level.
- A.Osman : Chemical & biological
studies of Garlic & Onion salad.
Hypoglycaemic effect.
- K.N.Shashikanth et al, Journal
of Food Science Technology, Vol.18,
March-April, 1981, Pg44 : Studies
on anti microbial & stimulatory
factors of Garlic.
- Kirtikar, K R and Basu, B D 1995.
Indian medicinal plants vol I.
- Kulkarni, K M Indian meteria medica
vol I
- Kakrani, H K 1981. Guggul, a reveiw.
Indian drugs 18 (12) : 417.
- Yamini, B et. al. 1984. Thyroid
stimulating action of Z-guggulsterone
obtained from Comiphora mukul. Planta
medica. : 78.
- Kotiyal, J P, Singh, D S and Bisht,
D B 1984. Gum guggul ( Comiphora
mukul ) fraction "A" in obesity
- A double blind clinical trial.
J. Res. Ay. Sid. vol VI (1, 3 and
4) : 20.
- Sidhu, L S et. al. 1976 Effect
of Gum guggul on body weight and
subcutaneous tissue folds. Jour.
Res. Ind. Yoga and Homeo 11 ; 2.
- Ahluvalia, P. and Amma, M K P
1988. Effect of oral ingestion of
oleo-resin of Gum guggul on the
fecal excreation of cholesterol
and bile acids in hypo and hypercholesterolimic
rats. Res. Bull ( Sci ) of Punjab
Univ. 39 (1-2) : 53.
- Baldwa, V S et. al. 1981. Comiphora
mukul ( Guggul), Garlic extract
and clofibrate in hypolipidemic
states. Rajesthan Medcinal Journal
20 (2) : 73.
- Singh, A K, Tripathi, S N and
Prasad, GG 1983. Response of Comiphora
mukul ( Guggulu ) on melatonin induced
hypo-thyroidism. Ancient science
of life III (2) : 85.
- Tripathi, S N et. al. 1984. Role
of Pushkara Guggulu in the management
of ischemic heart disease. Ancient
Science of life IV (1) : 9.
- Mester, L., Mister, M and Nityanand,
S 1979. Inhibition of platelet aggregation
by Guggulu steroids. Planta Medica
37 : 369.
- Studies on Guggulu,CCRAS; New
Delhi, 1989
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