| INTRODUCTION:
 North
America has one of the highest heart disease
rates in the world. Since 1940 cardiovascular
disease(CVD) has been the leading cause
of mortality and morbidity in the region.
It is estimated that over 56 million Americans
have some form of CVD. Although CVD is increasingly
common as people age, it is not an inevitable
consequence of the aging process. Atherosclerosis
and other forms of CVD are almost non existent
in some countries, even in elderly citizens.
However when these people migrate to the
US and consume a western diet, their risk
of CVD increases to match that of someone
born in the US. In addition , as developing
countries gain affluence and convert from
grain based to high -fat diets, the incidence
of CVD escalates.
It is seen from the above fact that dietary
factor influence the risk of CVD. Since
an entire population cannot change dietary
habits ( most of which are based on aggressive
marketing by huge consumer food companies),
it has become imperative for the population
to have remedies to counter this disease.
Modern medicine has no answers and those
offered by it have strong side effects.
A trade off is inevitable and some times
the side effects are greater than the benefit.
The expansion of genetically modified food
crops to rural economies in the third world
has brought the problems of the western
world to the door step of third world countries
poorly equipped to deal with changes in
lifestyles.
A summary of factors leading to hardening
of the arteries and heart disease
Unhealthy diet high in saturated fats
High blood pressure
Stressful lifestyles
Smoking (up to 300% higher)
Obesity
Lack of exercise
RECOMMENDATIONS:
Consume a high fiber diet with plenty of
fresh fruits and vegetables.
Reduce animal fats, red meat, fried and
processed foods, white sugar and salt.
Reduce caffeine, avoid smoking and alcohol.
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THE PRODUCT:
AV CIRCULO contains the most well documented
Asian herbs for protecting the heart and
improving heart function. These herbs produce
an improvement in blood flow to the heart
and stabilize the rate of heart contraction
and blood pressure when taken regularly.
AV CIRCULO has been the subject of clinical
studies and offers the best protection for
our heart and provides a natural alternative
to life long drug therapy and its unwanted
side effects. If necessary, it should be
combined with AV UNILIPID for complete cholesterol
control.
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COMPOSITION:
Each Capsule of AV ASMO contains extracts
of :
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RESEARCH:
Evaluation
of AV CIRCULO"S role in myocardial
necrosis in rats
Terminalia
arjuna bark
This herb has been conclusively proven to
have heart protective and blood pressure
lowering activity. Studies have shown that
extracts relieved heart pain and lowered
blood pressure. It has also been shown to
improve irregular palpitations. It increases
the force of contraction and assists the
nutrient supply to the heart, resulting
in the heart muscle gaining energy and the
number of heartbeats is reduced.
Crategus oxycantha
The fruits are cardiotonic, coronary vasodilator.
It is reputed to dissolve deposits in thickened
and sclerotic arteries. Various clinical
studies reveal increased cardiac performance
and output: decrease in peripheral vascular
resistance; decrease in pulmonary arterial
and capillary pressures; reductions in blood
pressure at rest and during exercise; and
improved metabolic parameters.This herb
improves circulation and nutrition to the
heart by dilating the coronary blood vessels.
Various clinical studies reveal increased
cardiac performance and reduction in blood
pressure at rest and during exercise.
Coleus forskholii
(Forskholin 4%)
Detailed pharmacological studies established
that forskohlin lowered normal or elevated
blood pressure in different animal species
through a vasodilatory effect and that it
had a positive intopic action on the heart
muscle . The antihypertensive effects of
forskohlin were attributed to a decrease
in peripheral resistance by action of the
drug on arteriolar smooth muscle. The positive
inotropic effects of forskohlin in the cardiac
muscle were shown to be initiated by stimulation
of the myocardium cell membrane adenylate
cyclase, followed by a rise in cyclic AMP,
an activation of membrane-bound protein
kinases, a lowering of the membrane bound
Na+, K+ -ATPase activity and activation
of the slow calcium gate, and an activation
of cytopalsmic protein kinases. Coleus Forskohlii,
shows that the plant kingdom offers excellent
prospects in the search for further potent
cardiac agents.
Boerhaavia
diffusa
The cardiovascular action of this herb has
been clinically studied. Due to its diuretic
activity it is specific for heart conditions
with fluid retention.
Withania somnifera
Withania somnifera has been variously described
as the most important medicinal plant in
India. It has been used in most preperations
due to it's confimed immunomodulatory action.
This herb has been the focus of hundreds
of clinical studies and is one of the most
exhaustively researched herbs. The anti-stress
activity of the roots of Withania somnifera
has been reported in multiple clinical studies.
Ashwagandha has been used in treatment of
most debilitating diseases.
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INDICATIONS:
- Hypertension
- Abnormal heart rhythms
- Tightness in the chest
- Heart palpitations
- Stress related heart symptoms
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DOSAGE:
2 capsule twice daily
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CONTRAINDICATIONS:
Not to be taken with conventional therapies.
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PREGNANCY:
Can be taken under medical supervision.
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REFERENCES:
- Burka J.F., Forskolin: Its chemical,
Biological and Medical Potential. Hoechst
India Ltd. 1986
- Ammon HPT and Muller AB, Forskolin:
From Ayurvedic remedy to a modern agent.
Planta Medica; 51: 474-7. 1985
- De Souza N.J., Forskolin – An example
of innovative drug research and natural
products. AF Harms(ED), Innovative approach
in drug research, Elsevier Science Publishers,
Amsterdam, pp. 191-207
- Heichergens h. Crataegus special extract
WS 1442 in cardiac insufficiency NYH A
1993
- Loew D, Phytotherapy in heart failure,
Phytomedicine 4:267-271, 1997
- Blesher V.R., Use of Crataegus in cardiology,
Fortscher Med. 15: 290-292 1992
- Oconolly et al, Treatment of the elderly,
multimorbid patients with stenocardiac
complaints with Crataegus. Therapiewoche
37: 3587-3600 1987
- Bharani A, et al, Salutray effect of
T. arjuna in patients with severe refractory
heart failure. Int. J.Cardiol. 49: 191-199.
1995
- Reichert R., Terminalia arjuna for Congestive
heart failure. Quarterly Rev. of Nat.
Med Fall: 177-178. 1996
- Divivedi S., et al. Terminalia arjuna
and prostaglandin E activity. Indian Drugs
24: 378-382. 1995
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